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GUARDIANS OF RENAL HEALTH: UNVEILING THE PROTECTIVE POTENTIAL OF TRIGONELLA FOENUM AGAINST ETHYLENE DIAMINE TETRA ACETIC ACID-INDUCED NEPHROTOXICITY IN MALE ALBINO RATS

Asenath Ibrahim , Damanhour University, Faculty of Science, Zoology department, Egypt

Abstract

This research investigates the protective potential of Trigonella Foenum against Ethylene Diamine Tetra Acetic Acid (EDTA)-induced nephrotoxicity in male albino rats. EDTA, a chelating agent commonly used in clinical settings, has been associated with renal damage. The study explores the therapeutic effects of Trigonella Foenum, a medicinal herb known for its antioxidant and anti-inflammatory properties, in mitigating EDTA-induced nephrotoxicity. Male albino rats are subjected to experimental conditions, and the administration of Trigonella Foenum is evaluated for its ability to preserve renal function and histological integrity. The findings shed light on the potential protective role of Trigonella Foenum in averting nephrotoxicity induced by EDTA exposure.

Keywords

Trigonella Foenum, Ethylene Diamine Tetra Acetic Acid, nephrotoxicity

References

Kalia K, S J Flora. (2005) Strategies for safe and effective therapeutic measures for chronic arsenic and lead poisoning. , Journal of occupational health 47, 1-21.

CSTEE (Scientific Committee on Toxicity, Ecotoxicity, and the Environment). (Opinionon the results of the Risk Assessment of:Tetrasodium EDTA and Edetic Acid (EDTA). Human Health Part. European Commission. , Brussels 1-7.

WHO. () Edetic acid (EDTA) in drinking-water. Background document for preparation of WHO Guidelines for drinking-water quality. Geneva, World Health Organization.

Frank R, Rau H. (1990) Photochemical transformation in aqueous solution and possible environmental fate of ethylenediaminetetraacetic acid (EDTA). Ecotoxicology and environmental safety. 19(1), 55-63.

Abd El-Ghany MA, Ramadan A M, Ghozy S F. (2012) Nutraceutical effects of curcuma, ginger, celery, yeast and honey on side effects of gentamicin induced nephrotoxicity in rats. , World Appl Sci J 16(5), 646-55.

Pydi R. (2012) Nephroprotective medicinal plants- A review. , Int J Univers Pharm Life Sci 1(2), 266-281.

N A Hamadouche, Slimani M, Merad-Boudia B, Zaoui C. (2009) Reproductive toxicity of lead acetate in adult male rats. , Am J Sci Res 3, 38-50.

Owoeye O, S K Onwuka. (2016) Lead Toxicity:. , Anatomy Journal of Africa 5(1), 783-794.

J P Peesa. (2013) Nephroprotective Potential of Herbal Medicines: A Review. , Asian J Pharm Tech 3(3), 115-118.

Acharya S, Srichamroen A, Basu S, Ooraikul B, Basu T. (2006) Improvement in the nutraceutical properties of fenugreek (Trigonella foenumgraecumL.). , Songklanakarin J Sci Technol; 28 (Suppl 1, 1-9.

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GUARDIANS OF RENAL HEALTH: UNVEILING THE PROTECTIVE POTENTIAL OF TRIGONELLA FOENUM AGAINST ETHYLENE DIAMINE TETRA ACETIC ACID-INDUCED NEPHROTOXICITY IN MALE ALBINO RATS. (2024). International Journal of Zoological Sciences, 4(01), 01-06. https://www.academicpublishers.org/journals/index.php/ijzs/article/view/211