Articles
| Open Access | OMEGA-3 FISH OIL MITIGATES IFOSFAMIDE TOXICITY IN MALE RATS
M. AZIZ , BIOLOGY DEPARTMENT, COLLEGE OF SCIENCE, SALAHADDIN UNIVERSITY, ERBIL, IRAQAbstract
This study investigates the protective potential of omega-3 fish oil against the toxicity of Ifosfamide, a chemotherapeutic agent, in male rats. Ifosfamide is known for its adverse effects on various organ systems, and its use in cancer treatment often leads to unwanted side effects. In this research, male rats were administered with Ifosfamide in the presence and absence of omega-3 fish oil supplementation. Various physiological and biochemical parameters were assessed to evaluate the protective role of fish oil against Ifosfamide-induced toxicity. The findings reveal that omega-3 fish oil has a mitigating effect on Ifosfamide toxicity, providing valuable insights into the use of dietary interventions to reduce chemotherapy-related side effects.
Keywords
Omega-3 fish oil, Ifosfamide toxicity, Chemotherapy side effects, Male rats, Protective role, Dietary intervention, Organ toxicity, Biochemical parameters
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