The increasing prevalence of antibiotic-resistant bacteria necessitates the development of alternative antimicrobial agents. Nano-structured polypyrrole (PPy) has emerged as a promising material due to its unique electrical and chemical properties, which can be enhanced through advanced synthesis techniques. In this study, we investigate the antibacterial activity of nano-structured polypyrrole synthesized via cyclic voltammetry (CV). Polypyrrole films were electrochemically polymerized onto electrode substrates using CV, optimizing parameters such as scan rate and polymerization potential to control the nanostructure and morphology of the resulting polypyrrole. The antibacterial properties of the nano-fabricated polypyrrole were assessed against common bacterial strains, including Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa, using standard disk diffusion and minimum inhibitory concentration (MIC) assays.

Our results reveal that the nano-structured polypyrrole exhibits significant antibacterial activity, with inhibition zones and MIC values indicating effective suppression of bacterial growth. The enhanced antibacterial performance is attributed to the increased surface area and reactive sites provided by the nanostructure, which facilitates greater interaction with bacterial cells. Additionally, the study explores the correlation between the polypyrrole's electrochemical properties and its antibacterial efficacy, providing insights into the mechanisms underlying its antimicrobial action. This research highlights the potential of cyclic voltammetry as a versatile method for fabricating nano-structured polypyrrole and suggests its applicability as an alternative antimicrobial agent. The findings offer a valuable contribution to the field of materials science and antimicrobial research, with implications for developing new strategies to combat bacterial infections.

Nano-structured polypyrrole, cyclic voltammetry, antibacterial activity

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