Articles | Open Access |

INTEGRATIVE FUNCTIONAL GENOMIC ANALYSIS OF HUMAN BRAIN DEVELOPMENT AND ASSOCIATED NEUROPSYCHIATRIC RISKS

Gavin Miller , Department of Neuroscience and Kavli Institute for Neuroscience, Yale School of Medicine, New Haven

Abstract

The human brain's development is a complex and highly orchestrated process influenced by a myriad of genetic factors. Disruptions in these processes can lead to various neuropsychiatric disorders. This study presents an integrative functional genomic analysis aimed at elucidating the genetic underpinnings of human brain development and their associations with neuropsychiatric risks. Utilizing advanced genomic technologies, including whole-genome sequencing, transcriptomics, and epigenomics, we identify key regulatory networks and genetic variants implicated in neurodevelopment. By integrating data from diverse cohorts and employing sophisticated bioinformatics tools, we map the interplay between genetic predispositions and environmental factors in the etiology of neuropsychiatric conditions. Our findings highlight novel genetic markers and pathways that may serve as potential targets for therapeutic interventions. This comprehensive analysis enhances our understanding of the genetic architecture of brain development and provides a foundation for future research into the prevention and treatment of neuropsychiatric disorders.

Keywords

Human brain development, Neuropsychiatric disorders, Functional genomics

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INTEGRATIVE FUNCTIONAL GENOMIC ANALYSIS OF HUMAN BRAIN DEVELOPMENT AND ASSOCIATED NEUROPSYCHIATRIC RISKS. (2025). International Journal of Data Science and Machine Learning, 5(01), 1-6. https://www.academicpublishers.org/journals/index.php/ijdsml/article/view/2194