Teaching Assistants (TAs), particularly in fields such as medical sciences, occupy a unique and critical position, serving as both learners and educators. Their professional ethics significantly influence the quality of education, clinical practice, and patient safety. Despite their pivotal role, TAs often face distinct challenges that can impact their adherence to ethical standards. This conceptual article aims to identify and elaborate on the multifaceted challenges hindering the optimal cultivation of professional ethics among teaching assistants and to propose effective strategies for their improvement. Drawing upon existing literature primarily from medical education and professional ethics, this paper synthesizes common stressors, educational gaps, and environmental factors that impede ethical conduct. Hypothetical solutions discussed include the implementation of comprehensive, integrated ethics curricula, robust mentorship and role-modeling programs, promotion of well-being initiatives, and the integration of dialogic and reflective assessment methods. By addressing these challenges through structured and sustained interventions, educational institutions can significantly enhance the professional ethical standards of their teaching assistants, thereby contributing to a higher quality of education and patient care.