Diseases of the oral mucosa are one of the most complex, urgent problems of dentistry, and to date they have been least studied in terms of etiology, pathogenesis, diagnosis and especially treatment among other dental diseases (Barer G.M., 2005; Rabinovich I.M., 2010).

At the moment, there are fairly accurate clinical criteria for the diagnosis of inflammatory periodontal diseases, there are a large number of different methods of treating gingivitis, which reflect the attempts of researchers and clinicians to have a therapeutic effect on various links in the pathogenesis of the pathological process (Gerasimovich L.M., 2003). However, despite the significant achievements of modern dentistry, the frequency of relapses of transition to the developed forms of inflammatory diseases remains high. Progressive lesion of the periapical tissues often leads to the loss of teeth and can be a source of many diseases (Bascones- Martinez A., 2005).

Therefore, the urgency of the problem of detection, diagnosis, treatment of gingivitis comes to the fore and requires careful study and search for ways and effective methods of providing dental care.

catarrhal gingivitis, oral mucosa, microbial flora periodontal disease, enzyme

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