Articles
| Open Access |
https://doi.org/10.55640/
EVALUATION OF THE EFFECTIVENESS OF USING LIPOSOMAL FORMS OF VITAMINS, USING VITAMIN C AS THE EXAMPLE
E. R. Tukhvatulina,M. J. Baltaeva , Tashkent Pediatric Medical InstituteAbstract
Vitamin C is an exogenous compound required for various metabolic processes; therefore, effective delivery is critical to maintaining body homeostasis. The pharmacokinetics of vitamin C and its low amounts in processed foods require its continuous supplementation. In this article, we present a review of a new liposomal vitamin C formulation free of harmful organic solvents. The formulation was quantitatively characterized in terms of its chemical composition and nanostructuring. Encapsulation of vitamins and minerals in liposomes helps improve overall bioavailability.
Keywords
Liposome, pharmacokinetics, bioavailability
References
J Manna S, Wu Y, Wang Y, et al. Probing the mechanism of bupivacaine drug release from multivesicular liposomes. Control Release. 2019; 279–287.
Patra JK, Das G, Fraceto LF, et al. Nano based drug delivery systems: recent developments and future prospects. J Nanobiotechnology. 2018;16(1):71
Manna S, Wu Y, Wang Y, et al. Probing the mechanism of bupivacaine drug release from multivesicular liposomes. J Control Release. 2019; 294:279–287.
Sreerag Gopi &Preetha Balakrishnan. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. Pages 356-364 | Received 19 May 2020, Accepted 28 Aug 2020, Published online: 06 Oct 2020.
Stephen Hickey,Hilary J. Roberts &Nicholas J. Miller. Pharmacokinetics of oral vitamin C. Pages 169-177 | Published online: 13 Jul 2009.
Sreerag Gopi &Preetha Balakrishnan. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. Pages 356-364 | Received 19 May 2020, Accepted 28 Aug 2020, Published online: 06 Oct 2020.
Shibuya N, Humphers JM, Agarwal MR, Jupiter DC. Efficacy and safety of high-dose vitamin C on complex regional pain syndrome in extremity trauma and surgery--systematic review and meta-analysis. J Foot Ankle Surg. 2013 Jan-Feb;52(1):62-6. Epub 2012 Sep 15.
Sercombe L, Veerati T, Moheimani F, et al. Advances and challenges of liposome assisted drug delivery. Front Pharmacol. 2015;6:286.
Shantanu PandeORCID Icon. Liposomes for drug delivery: review of vesicular composition, factors affecting drug release and drug loading in liposomes. Pages 428-440 | Received 18 May 2023, Accepted 07 Aug 2023, Published online: 18 Aug 2023
Article Statistics
Downloads
Copyright License
This work is licensed under a Creative Commons Attribution 4.0 International License.