
PARKINSON'S DISEASE: DEVELOPMENT MECHANISMS AND MODERN CORRECTION METHODS
Zaynieva Makhbuba,Murodillayeva Sabrina,Izzatillayeva Sabina,Kuziev Sherali , National University of UzbekistanAbstract
Parkinson's disease (PD) is a progressive neurodegenerative disease of the central nervous system, manifested by movement disorders and symptoms of immobility. The relevance of the disease is determined by its prevalence, disability, and high socio-economic burden. The main pathophysiological mechanism of PD is the progressive loss of dopaminergic neurons in the substantia nigra pars compacta, which leads to dopamine deficiency in the striatum. The purpose of this thesis is to analyze the mechanisms of development of PD and modern methods of correction.
Keywords
Parkinson's disease, rotenone
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