Acne vulgaris is one of the most common dermatological conditions affecting both adolescents and adults. In recent decades, significant advances have been made in the treatment of acne due to the development of new pharmacological agents and the implementation of modern device-based therapies. This article reviews current treatment strategies, including the use of topical and systemic retinoids, antibiotics, hormonal therapy, as well as laser and photodynamic therapies. Special attention is given to the importance of a comprehensive and personalized approach based on the severity of the condition, skin type, and the patient’s overall health. Additionally, the paper explores emerging trends in acne management such as the role of the skin microbiome, probiotics, and targeted molecular therapies.

acne, acne treatment, retinoids, isotretinoin, laser therapy, photodynamic therapy, hormonal therapy, skin microbiome, dermatocosmetology, post-acne

Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., ... & Bhushan, R. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973. https://doi.org/10.1016/j.jaad.2015.12.037

Kurokawa, I., Danby, F. W., Ju, Q., Wang, X., Xiang, L. F., Xia, L., ... & Thiboutot, D. (2009). New developments in our understanding of acne pathogenesis and treatment. Experimental Dermatology, 18(10), 821–832. https://doi.org/10.1111/j.1600-0625.2009.00924.x

Dreno, B., Pecastaings, S., Corvec, S., Veraldi, S., Khammari, A., & Roques, C. (2018). Cutibacterium acnes (Propionibacterium acnes) and acne vulgaris: a brief look at the latest updates. Journal of the European Academy of Dermatology and Venereology, 32(S2), 5-14. https://doi.org/10.1111/jdv.14893

Thiboutot, D., & Gollnick, H. (2009). Acne: pathogenesis, clinical features, and treatment. In: Bolognia J.L., Jorizzo J.L., Rapini R.P. (Eds.), Dermatology (2nd ed.). Elsevier.

Dawson, A. L., & Dellavalle, R. P. (2005). Acne vulgaris. BMJ, 330(7493), 940–944. https://doi.org/10.1136/bmj.330.7493.940

Zaenglein, A. L. (2018). Acne vulgaris. New England Journal of Medicine, 379(14), 1343-1352. https://doi.org/10.1056/NEJMcp1702493