Articles | Open Access | https://doi.org/10.55640/

COMPARATIVE MORPHOLOGICAL AND MORPHOMETRIC INDICATORS OF MAJOR SALIVARY GLANDS UNDER CHRONIC EXPOSURE TO GAS

Usmonov Sojiddin Saloxiddinovich,Namazov Farrux Jumayevich ,

Abstract

This scientific study investigates morphological and morphometric changes in the major salivary glands of laboratory animals under chronic exposure to NO₂ and SO₂ gases. The histological structure of the parotid, submandibular, and sublingual salivary glands was analyzed using microscopic and morphometric methods. The results revealed cellular and tissue-level degeneration, inflammation, atrophic changes, and a decrease in secretory activity. These changes reflect the adverse effects of the gas mixture and emphasize the need for preventive measures to ensure environmental safety.

Keywords

References

Abdullayev, A.Sh., & Karimov, J.B. (2018). The effects of atmospheric gases on the organism. Tashkent: Fan va texnologiya Publishing.

Otabekov, A.T., & Raximov, Z.Z. (2020). Morphological features and pathology of salivary glands. Scientific Journal of Tashkent Medical Academy, 3(45), 67–73.

Park, Y., et al. (2019). Effect of nitrogen dioxide on salivary gland morphology in rats. Journal of Toxicologic Pathology, 32(4), 287–295. https://doi.org/10.1293/tox.2019-0023

World Health Organization (WHO). (2018). Ambient air pollution: Health impacts. https://www.who.int/news-room/fact-sheets/detail/ambient-(outdoor)-air-quality-and-health

Ganiev, B.O., & Tursunov, M.R. (2017). The dependence of salivary gland activity on ecological factors. Uzbekistan Medical Journal, (2), 44–48.

Sun, H., et al. (2021). Chronic exposure to sulfur dioxide causes salivary gland dysfunction via oxidative stress mechanisms. Environmental Science and Pollution Research, 28(16), 19911–19919. https://doi.org/10.1007/s11356-020-11909-x

Mahkamov, F.M. (2015). Morphological indicators of the body’s response to ecological stress. Tashkent: Academy of Sciences of the Republic of Uzbekistan.

Zhang, Q., et al. (2016). Air pollution and salivary antioxidant system alteration. Environmental Research, 146, 218–226. https://doi.org/10.1016/j.envres.2016.01.019

Sirojiddinov, A.S., & Karimova, L.U. (2019). Morphology and functional significance of salivary glands. Problems of Medicine and Biology, (1), 51–57.

Kuo, Y.C., et al. (2020). Long-term effects of air pollutants on oral tissues: A histological study. Toxicology Letters, 331, 1–7. https://doi.org/10.1016/j.toxlet.2020.05.008

Article Statistics

Downloads

Download data is not yet available.

Copyright License

Download Citations

How to Cite

COMPARATIVE MORPHOLOGICAL AND MORPHOMETRIC INDICATORS OF MAJOR SALIVARY GLANDS UNDER CHRONIC EXPOSURE TO GAS. (2025). International Journal of Medical Sciences, 5(07), 90-92. https://doi.org/10.55640/