Biorevitalization has emerged as a minimally invasive technique in aesthetic dermatology aimed at restoring skin hydration and promoting dermal regeneration to counteract signs of aging. This review synthesizes current knowledge regarding the mechanisms of action, clinical efficacy, safety profile, and procedural techniques of biorevitalization, with a focus on hyaluronic acid-based formulations enriched with bioactive compounds. Clinical evidence indicates improvements in skin elasticity, texture, and hydration following treatment, though methodological limitations in existing studies necessitate cautious interpretation. Safety data suggest a favorable profile with primarily mild and transient adverse effects. Key challenges include heterogeneity of products, lack of standardized protocols, and insufficient high-quality randomized trials. Future research directions emphasize the development of advanced biomaterials, mechanistic elucidation, and personalized therapeutic approaches to optimize outcomes. Overall, biorevitalization holds promise as a valuable adjunct in anti-aging therapies within cosmetology, warranting further rigorous investigation.

Biorevitalization, anti-aging, aesthetic dermatology, skin rejuvenation, hyaluronic acid, mesotherapy

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