Endometrial hyperplastic processes represent a group of proliferative conditions of the endometrium that range from benign glandular-stromal overgrowth to precancerous atypical hyperplasia. They are considered one of the most significant gynecological disorders due to their potential progression to endometrial carcinoma. Early diagnosis and adequate treatment are essential to prevent malignant transformation while maintaining reproductive potential. Recent advancements in imaging techniques, molecular diagnostics, and fertility-preserving treatment options have significantly transformed the clinical approach to endometrial hyperplasia. This article provides a comprehensive overview of the current strategies for early detection and treatment, emphasizing personalized medicine and evidence-based management.

Endometrial hyperplasia; atypical hyperplasia; early diagnosis; hysteroscopy; endometrial biopsy; progestin therapy; levonorgestrel intrauterine system; fertility preservation; molecular markers; endometrial carcinoma prevention.

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