Articles | Open Access | https://doi.org/10.55640/

THE INFLUENCE OF MELATONIN ON SEX HORMONES

Jamolova Unsunoy Javlonbek qizi , Asian International University (Bukhara,Uzbekistan)

Abstract

Melatonin, a hormone synthesized by the pineal gland, is primarily known for its role in regulating circadian rhythms and sleep–wake cycles. However, emerging evidence indicates that melatonin also influences reproductive physiology by modulating the secretion of sex hormones. This article reviews the current scientific data concerning the effects of melatonin on estrogen, progesterone, and testosterone synthesis, as well as its physiological and clinical implications for reproductive health.

Keywords

Melatonin, Sex hormones, Estrogen, Testosterone, Circadian rhythm, Reproductive health

References

Reiter, R. J., Tan, D. X., Korkmaz, A., & Ma, S. (2014). Melatonin and Reproductive Physiology: An Overview. Endocrine Reviews, 35(2), 101–134.

Tamura, H., Nakamura, Y., Korkmaz, A., & Sugino, N. (2012). Melatonin and the Ovary: Physiological Roles and Clinical Implications. Fertility and Sterility, 98(6), 1528–1537.

Luboshitzky, R., et al. (2001). Relationship between Nocturnal Melatonin Levels and Reproductive Hormones in Normal Men. Journal of Clinical Endocrinology & Metabolism, 86(2), 630–634.

Pandi-Perumal, S. R., et al. (2006). The Role of Melatonin in Reproductive Physiology. Neuro Endocrinology Letters, 27(4), 423–431.

Jahan, S., et al. (2021). Melatonin: A Multifaceted Hormone Regulating Female Reproductive Health. Frontiers in Endocrinology, 12, 688–695.

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THE INFLUENCE OF MELATONIN ON SEX HORMONES. (2025). International Journal of Medical Sciences, 5(11), 148-149. https://doi.org/10.55640/