In this study, the effects of the plant-based biologically active supplements “As-Sabr” and “As-Sedan” on the nervous system were evaluated in vivo based on catalase, superoxide dismutase (SOD), malondialdehyde (MDA), and diene conjugate (DC) biomarkers in an AlCl₃-induced neurotoxic model. Experiments conducted on 30 laboratory rats demonstrated that the neurotoxic model caused a decrease in antioxidant enzyme activity and an increase in lipid peroxidation markers. In the groups receiving the supplements, catalase and SOD activity increased, while MDA and DC levels decreased, and protein metabolism was restored. The obtained results confirmed the neuroprotective and antioxidant properties of these supplements.

nervous system; catalase; superoxide dismutase (SOD); malondialdehyde (MDA); diene conjugates (DC); lipid peroxidation; antioxidant defense; “As-Sabr”; “As-Sedan”; in vivo model

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