Articles
| Open Access |
https://doi.org/10.55640/
THE IMPORTANCE OF ENDEMIC MUMPS IN CHILDREN AND MODERN TREATMENT METHODS
Kholmurodov Inoyatullo Ismatulloyevich, Ziyodullayeva Zarina Akmal kizi , Termiz University of Economics and ServiceAbstract
Endemic mumps (rubella, mumps) is the pathology that has decreased most sharply among childhood infectious diseases since the introduction of the MMR vaccine, but in 2023-2025, "breakthrough" infections in vaccinated children (vaccine breakthrough) and the need for a third dose have become an urgent problem. This article highlights the clinical and epidemiological characteristics of the disease in children, unique complications (type 1 diabetes, fetal death, sensorineural deafness), and modern treatment and prevention algorithms from a medical perspective. New medical facts: the mumps virus can cause autoimmune type 1 diabetes by directly cytolytically affecting pancreatic β-cells (2024 cohort studies); also, the oncogenic potential of the virus (association with Warthin tumors of the parotid gland) is being reassessed from the perspective of pediatric oncology.
Keywords
Endemic mumps in children, Mumps virus infection, Painful swelling of the parotid gland, Involvement of the submandibular and sublingual glands, Aseptic meningitis and encephalitis, Pancreatitis and pancreatic injury, Orchitis and reproductive complications, Sensorineural hearing loss, Clinical diagnosis and laboratory confirmation, RT-PCR and serological tests, IgM and IgG antibodies, Modern treatment methods and symptomatic therapy, Analgesics and fever control, Supportive measures, Bacterial superinfection and antibiotics, Efficacy and prevention of MMR vaccine
References
Davison P., et al. Mumps. StatPearls [Internet]. 2024. (StatPearls review of the general description and pathogenesis of mumps).
Centers for Disease Control and Prevention (CDC). Mumps: Clinical Diagnosis Fact Sheet and Vaccine Considerations. (Official information on the effectiveness and clinical diagnosis of the MMR vaccine).
Wu H. et al. Mumps Orchitis: Clinical Aspects and Mechanisms. (Review on Orchitis and Reproductive Consequences).
ECDC. Mumps Annual Epidemiological Report for 2022. (European epidemiological reports and recommendations).
Treatment & Management (clinical 5. Medscape/eMedicine: Mumps management and recommendations for severe complications).
Johns Hopkins ABX Guide: Parotitis (clinical information on bacterial parotitis and antibiotic approaches).
G.A. Ganiyevich et al. Outpatient polyclinic pediatrics (2024).
Shermatov R.M. Pediatrics (textbook).
Ministry of Health of the Republic of Uzbekistan. Clinical guidelines for immunoprophylaxis against rubella, mumps and measles, 2024.
Di Pietro GM, et al. Mumps virus and Warthin tumor: new oncogenic link? JAMA Otolaryngol Head Neck Surg. 2025.
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