Articles
| Open Access |
https://doi.org/10.55640/
THE RELATIONSHIP BETWEEN DIABETES MELLITUS AND ISCHEMIC HEART DISEASE
Tursunboyeva Barnoxon Akmaljon kizi, Joʻraboyev Ahmadjon Anvarjon ugli, Moydinova Oyistaxon Fayzulla kizi, Maxamadjonov Obidjon Xurshidbek ugli , Kokand University Andijan branchAbstract
This article analyzes the relationship between diabetes mellitus (DM) and ischemic heart disease (IHD) from clinical, epidemiological, and pathophysiological perspectives. The study results show that patients with diabetes have a 2–4 times higher risk of developing cardiovascular complications, particularly ischemic heart disease. Dyslipidemia, hyperglycemia, insulin resistance, endothelial dysfunction, and oxidative stress are the main pathogenetic mechanisms of this process.
Keywords
diabetes mellitus, ischemic heart disease, atherosclerosis, insulin resistance, hyperglycemia, dyslipidemia.
References
International Diabetes Federation. IDF Diabetes Atlas, 10th Edition, 2024.
World Health Organization. Global Report on Diabetes, Geneva, 2023.
UKPDS Group. Intensive blood-glucose control and risk of vascular complications, Lancet, 2023.
Framingham Heart Study, 2022.
American Heart Association. Diabetes and Cardiovascular Risk, Circulation, 2023.
Tashkent Medical Academy. Epidemiological surveillance of diabetes and ischemic heart disease, 2024.
DeFronzo R. et al. Pathophysiology of Type 2 Diabetes and Cardiovascular Damage, Diabetologia, 2023.
Article Statistics
Downloads
Copyright License
This work is licensed under a Creative Commons Attribution 4.0 International License.