Articles | Open Access | https://doi.org/10.55640/

STRUCTURAL ORGANIZATION OF THE HUMAN HEART AND ITS FUNCTIONAL ZONES: CLINICAL SIGNIFICANCE

Ibrokhimjonova Mumtozbegim ,
Qosimova Xilola ,

Abstract

The human heart is a complex, four-chambered muscular organ responsible for maintaining continuous blood circulation and supporting systemic and pulmonary functions. This descriptive review examines the anatomical structure and functional zones of the heart, including its chambers, myocardial layers, valves, coronary circulation, and conduction system. The study synthesizes current literature to highlight the relationship between structural integrity and functional efficiency, emphasizing the clinical significance of anatomical variations in conditions such as arrhythmias, valvular disorders, myocardial infarction, and heart failure. The findings reinforce the importance of comprehensive knowledge of cardiac anatomy for medical education, early diagnosis, and effective management of cardiovascular diseases. Understanding the interplay between structure and function is essential for optimizing patient outcomes and guiding clinical interventions.

Keywords

Human heart; Cardiac anatomy; Functional zones; Chambers; Valves; Conduction system; Coronary circulation; Cardiovascular diseases

References

Marieb, E. N., & Hoehn, K. (2018). Human Anatomy & Physiology. Pearson Education.

Moore, K. L., Dalley, A. F., & Agur, A. M. R. (2022). Clinically Oriented Anatomy. Wolters Kluwer

Lilly, L. S. (2021). Pathophysiology of Heart Disease: A Collaborative Project of Medical Students and Faculty. Wolters Kluwer.

World Health Organization. (2024). Cardiovascular Diseases: Key Facts. WHO Publication.

Sadler, T. W. (2020). Langman’s Medical Embryology. Wolters Kluwer.

Tortora, G. J., & Derrickson, B. (2017). Principles of Anatomy and Physiology. Wiley.

Guyton, A. C., & Hall, J. E. (2020). Textbook of Medical Physiology. Elsevier.

Netter, F. H. (2019). Atlas of Human Anatomy. Elsevier.

American Heart Association. (2023). Heart Disease and Stroke Statistics. AHA Scientific Update.

Braunwald, E. (2022). Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. Elsevier.

Hurst, J. W., & Fuster, V. (2019). Hurst’s The Heart. McGraw-Hill Education.

Jameson, J. L., Fauci, A. S., Kasper, D. L., Hauser, S. L., & Loscalzo, J. (2018). Harrison’s Principles of Internal Medicine. McGraw-Hill Education.

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STRUCTURAL ORGANIZATION OF THE HUMAN HEART AND ITS FUNCTIONAL ZONES: CLINICAL SIGNIFICANCE. (2025). International Journal of Medical Sciences, 5(11), 1213-1218. https://doi.org/10.55640/