Microcurrent therapy, involving the application of ultra-low electrical currents, has garnered increasing attention for its potential therapeutic applications in the management of diverse medical conditions. This study presents a report on twelve cases where microcurrent therapy was employed for the management of diabetes mellitus, hypertension, and chronic wounds. The cases illustrate notable improvements in symptom management and wound healing. Additionally, this study delves into the mechanisms of action underlying microcurrent therapy, exploring its potential to modulate cellular processes, enhance blood flow, and promote tissue repair. Keywords: Microcurrent therapy, Diabetes mellitus, Hypertension, Chronic wounds, Mechanism of action, Case report, Therapeutic potential.