This study explores the utilization of the antidiabetic alkaloid Glycosin in tablet formulations, aiming to provide an effective therapeutic option for diabetes management. Glycosin, derived from natural sources, exhibits promising antidiabetic properties, making it an attractive candidate for pharmaceutical development. In this research, we present the formulation and comprehensive evaluation of Glycosin-based tablets, assessing their pharmacokinetic properties, stability, and therapeutic efficacy. The study sheds light on the potential of Glycosin as an innovative approach to antidiabetic treatment.