Anemia among adolescents is a pervasive public health concern with multifactorial determinants. This study seeks to uncover the prevalence and factors associated with anemia in a border region of West Bengal, India, focusing on adolescents. A cross-sectional survey was conducted, involving a representative sample of adolescents living in the border areas. Hemoglobin levels were measured, and structured interviews were employed to collect data on demographic, dietary, and health-related factors. Statistical analysis, including logistic regression, was used to identify correlates of anemia. The findings reveal a substantial prevalence of anemia among adolescents in this border region, with factors such as nutritional deficiencies, socioeconomic status, and gender emerging as significant determinants. This study contributes valuable insights into the anemia burden among adolescents in border regions and provides a foundation for targeted interventions to address this pressing health issue.