Articles
| Open Access | DETERMINING THE ROLE OF MMP-9 AND TIMP-1 POLYMORPHIC GENES IN SARS COV-2 INDUCED MYOCARDITIS.
Akhmedova Gulchehra Abdullaevna, Aminov Feruz Ravshanbekovich, Rasulov Rakhmatillo Saydullayevich , Assistant, PhD Department of Internal Medicine No.1 named Associate Professor N. A.Abdullayev, Samarkand State Medical University. Student of group 604, Faculty of Medical Pedagogy, Samarkand State Medical University. Maxillofacial surgeon at the Samarkand branch of the Republican Scientific and Practical Center of Traumatology and Orthopedics.Abstract
Current evidence suggests that MMP and TIMP gene polymorphisms may have a significant impact on the degree of inflammation and structural changes in the myocardium during viral infections, including COVID-19. However, the results of studies remain contradictory due to differences in study groups, methodologies, and evaluation criteria. In addition, most of the studies have focused on general aspects of inflammation in myocarditis, and the exact mechanisms associated with genetic variants in the MMP and TIMP genes are poorly understood.
Keywords
coronavirus disease 2019, severe acute respiratory syndrome virus, matrix metalloproteinas, tissue inhibitor of matrix metalloproteinas.
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