Articles | Open Access |

PHYTOCHEMICAL ANALYSIS AND EVALUATION OF PHARMACEUTICAL INDICATORS OF PAEONIA LACTIFLORA AND GINKGO BILOBA

Xolboyev Yusufjon Xakimovnch , Scientific supervisor
Shodmonaliyev Abdulaziz Azamatjon ugli , Master’s Student

Abstract

 Medicinal plants play an important role as sources of biologically active compounds in the pharmaceutical industry. This study is aimed at analyzing the phytochemical composition of Paeonia lactiflora and Ginkgo biloba and evaluating their pharmaceutical parameters. In the course of the study, Paeonia lactiflora roots and Ginkgo biloba leaves were used as plant raw materials.

The results of the phytochemical analysis revealed the presence of flavonoids, phenolic compounds, and glycosides in both plants. Ginkgo biloba was distinguished by its high content of flavonoids and phenolic compounds, while Paeonia lactiflora showed a high level of monoterpene glycosides, particularly paeoniflorin. The presence of the main biologically active compounds was confirmed using thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).

During the evaluation of pharmaceutical parameters, moisture content, total ash, and extractive values were determined, and their compliance with pharmacopoeial requirements was confirmed. The obtained results indicate that Paeonia lactiflora and Ginkgo biloba are promising for use in pharmaceutical practice.

Keywords

Paeonia lactiflora; Ginkgo biloba; phytochemical analysis; biologically active compounds; flavonoids; phenolic compounds; pharmaceutical parameters.

References

World Health Organization. WHO guidelines on good agricultural and collection practices (GACP) for medicinal plants. Geneva: WHO; 2003.

Evans WC. Trease and Evans’ Pharmacognosy. 16th ed. Edinburgh: Saunders Elsevier; 2009.

He DY, Dai SM. Anti-inflammatory and immunomodulatory effects of paeoniflorin and total glucosides of Paeonia lactiflora. Pharmacol Ther. 2011;130(1):13–20.

Mahadevan S, Park Y. Multifaceted therapeutic benefits of Ginkgo biloba L.: chemistry, efficacy, safety, and uses. J Food Sci. 2008;73(1):R14–R19.

Smith JV, Luo Y. Studies on molecular mechanisms of Ginkgo biloba extract. Appl Microbiol Biotechnol. 2004;64(4):465–472.

Chinese Pharmacopoeia Commission. Pharmacopoeia of the People’s Republic of China. Beijing: China Medical Science Press; 2020.

Wagner H, Bladt S. Plant Drug Analysis: A Thin Layer Chromatography Atlas. 2nd ed. Berlin: Springer; 2001.

Harborne JB. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. 3rd ed. London: Chapman & Hall; 1998.

European Pharmacopoeia Commission. European Pharmacopoeia. 10th ed. Strasbourg: Council of Europe; 2020.

Gupta VK, Sharma SK. Plants as natural antioxidants: phytochemical and pharmacological perspectives. Nat Prod Res. 2014;28(20):1795–1807.

Article Statistics

Downloads

Download data is not yet available.

Copyright License

Download Citations

How to Cite

PHYTOCHEMICAL ANALYSIS AND EVALUATION OF PHARMACEUTICAL INDICATORS OF PAEONIA LACTIFLORA AND GINKGO BILOBA. (2026). International Journal of Artificial Intelligence, 6(02), 3-9. https://www.academicpublishers.org/journals/index.php/ijai/article/view/10612