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| Open Access | ANTIBIOTIC RESISTANCE AS A GLOBAL CLINICAL CHALLENGE: FROM MOLECULAR MECHANISMS TO BEDSIDE PRACTICE
Mavlonova Muhayyo Qahramon kizi, Suyunov Farrux Sayfullo ugli, Murtozoyeva O'g'iloy Saydulla kizi, Obloberdiyev Muxammad Komil ugli, Nizamitdinova Shaxzoda Djamshedovna , 4th-year studentof the Faculty of Pediatrics, Samarkand State Medical University, 5th-year student of the Faculty of Pediatrics, Samarkand State Medical University, 6th-year students of the Faculty of Pediatrics, 3th-year student of the Faculty of PediatricsAbstract
Antibiotic resistance has emerged as one of the most critical challenges facing modern medicine. The increasing prevalence of resistant bacterial pathogens threatens the effectiveness of standard antimicrobial therapies and compromises clinical outcomes across a wide range of infectious diseases. This article explores antibiotic resistance as a multidimensional clinical problem, linking molecular mechanisms of resistance with their direct implications for diagnosis, treatment, and patient care. Emphasis is placed on the importance of rational antibiotic use and evidence-based decision-making at the bedside to combat the growing burden of resistant infections.
Keywords
Antibiotic resistance; antimicrobial resistance; bacterial pathogens; molecular mechanisms; clinical practice; treatment failure; rational antibiotic therapy; global health.
References
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