Articles
| Open Access | MOLECULAR AND FUNCTIONAL MECHANISMS OF CARDIAC PATHOPHYSIOLOGY: FROM CELLULAR INJURY TO ORGAN DYSFUNCTION
Rakhimov Khamidullo Odiljonovich , Assistant, Department of Pathological Physiology, Andijan State Medical InstituteAbstract
Background: Cardiac pathophysiology is driven by a complex interaction of molecular, structural, and systemic factors that impair myocardial performance.
Keywords
cardiac pathophysiology, ischemia-reperfusion injury, ventricular remodeling, mitochondrial dysfunction, calcium signaling, heart failure.
References
Neubauer S. Mechanisms of cardiac dysfunction. Lancet. 2021;397:1383–1396.
Yellon DM, Hausenloy DJ. Ischemia-reperfusion injury. N Engl J Med. 2020;382:1124–1136.
Hill JA, Olson EN. Cardiac hypertrophy and remodeling. Annu Rev Physiol. 2019;81:623–648.
Bers DM. Calcium cycling in the failing heart. Circ Res. 2021;128:1108–1124.
Murphy E, Steenbergen C. Mitochondrial injury in cardiac pathophysiology. Circ Res. 2020;126:284–295.
Article Statistics
Downloads
Copyright License

This work is licensed under a Creative Commons Attribution 4.0 International License.