Articles
| Open Access | DISTRIBUTION AND CHARACTERISTICS OF HEMOSTASIS SYSTEM DISORDERS IN DISSEMINATED INTRAVASCULAR COAGULATION OF VARIOUS GENESIS
Zaynutdinova Dilafruz Latibovna,Berdiyorova Moxinur Ulug‘bek qizi , Tashkent State Medical InstituteAbstract
This scientific study presents data on the prevalence, global occurrence, causes, origin, and characteristics of hemostatic disorders in disseminated intravascular coagulation (DIC) of various genesis.
Keywords
hemostasis system, DIC syndrome, hypocoagulation, hypercoagulation.
References
1 - Adelborg K, Larsen JB, Hvas AM. Disseminated intravascular coagulation: epidemiology, biomarkers, and management. Br J Haematol. 2021 Mar;192(5):803-818. doi: 10.1111/bjh.17172. Epub 2021 Feb 8. PMID: 33555051
2 - Ahsanullah Unar, Lorenzo Bertolino, Decoding Sepsis-Induced Disseminated Intravascular Coagulation: A Comprehensive Review of Existing and Emerging Therapies, J. Clin. Med. 2023, 12(19), 6128; https://doi.org/10.3390/jcm12196128
3 - Iba T, Levi M, Thachil J, Levy JH. Disseminated Intravascular Coagulation: The Past, Present, and Future Considerations. Semin Thromb Hemost. 2022 Nov;48(8):978-987. doi: 10.1055/s-0042-1756300. Epub 2022 Sep 13. PMID: 36100234
4 - Iba T, Maier CL, Scarlatescu E, Levy JH. Introducing the New Definition and Diagnostic Criteria of Disseminated Intravascular Coagulation Released by the International Society on Thrombosis and Haemostasis in 2025. Semin Thromb Hemost. 2025 Aug 19. doi: 10.1055/a-2675-6068. Epub ahead of print. PMID: 40829630
5 - Iba, T., Helms, J., Connors, J.M. et al. The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation. j intensive care 11, 24 (2023). https://doi.org/10.1186/s40560-023-00672-5
6 - Kiya GT, Abebe G, Mekonnen Z, Tadasa E, Milkias G, Asefa ET. A comparison of disseminated intravascular coagulation scoring systems and their performance to predict mortality in sepsis patients: A systematic review and meta-analysis. PLoS One. 2025 Jan 16;20(1):e0315797. doi: 10.1371/journal.pone.0315797. PMID: 39821194; PMCID: PMC11737756.
7 - Nishita, Y., Taga, M., Sakurai, M. et al. Prognostic factors in patients with septic disseminated intravascular coagulation treated with thrombomodulin: the effect of reduced thrombomodulin dose; a single-center, retrospective, observational study. J Pharm Health Care Sci 8, 32 (2022). https://doi.org/10.1186/s40780-022-00264-9
Article Statistics
Downloads
Copyright License

This work is licensed under a Creative Commons Attribution 4.0 International License.