Articles | Open Access |

MECHANISMS OF IONIZING RADIATION-INDUCED DAMAGE TO CELLS AND DNA

Kholmetov Shavkat Sherimatovich, Fayziyeva Nodira Alisherovna , Tashkent State Technical University Department of Biomedical Engineering, Biophysics and Informatics Assistant:
Orazbaev Nuraliy Amanaliyevich, Rustamov Sanjar Rustam ugli , 2nd Faculty of General Medicine, 1st-year student
Kudaibergenov Sultan Polatovich , Pediatrics Program, 1st-year student

Abstract

This article analyzes the primary physical and biological effects of ionizing radiation on living cells. Radiation-induced DNA damage, disruption of cellular structures, and the mechanisms of their repair are explained based on scientific evidence. Additionally, risk factors associated with the use of radiation sources in medical practice and the main methods of radiation protection aimed at minimizing these risks are discussed. The results hold practical significance in the fields of biophysics, radiobiology, and medical diagnostics.

Keywords

Ionizing radiation, radiobiological effects, DNA damage, cellular processes, radiation dose, safety standards, X-ray, radiotherapy, mutagenesis, ionization process.

References

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Hall, E. J., & Giaccia, A. J. (2012). Radiobiology for the Radiologist (7th ed.). Philadelphia: Lippincott Williams & Wilkins.

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MECHANISMS OF IONIZING RADIATION-INDUCED DAMAGE TO CELLS AND DNA. (2025). International Journal of Artificial Intelligence, 5(12), 543-547. https://www.academicpublishers.org/journals/index.php/ijai/article/view/8607