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| Open Access | HISTOGENESIS OF THE MALE REPRODUCTIVE SYSTEM
Bekjanova. G.M , Candidate of medical sciences senior teacher of the department of Medical biological sciences, EMU UniversityAbstract
Histogenesis of the male reproductive system is a tightly coordinated developmental sequence in which genetic sex determination is translated into organ-level differentiation of the testes, the ductal system, accessory glands, and external genitalia. The process begins with formation of the urogenital ridge and migration of primordial germ cells, proceeds through testis determination driven by a somatic cell program, and culminates in androgen- and peptide-mediated remodeling of embryonic ducts and the urogenital sinus.
Keywords
histogenesis, testis development, Sertoli cells, Leydig cells, Wolffian duct, prostate development.
References
Moore K. L., Persaud T. V. N., Torchia M. G. The Developing Human: Clinically Oriented Embryology. 11th ed. Philadelphia: Elsevier, 2020. opac.kwiu.edu.ge
Sadler T. W. Langman’s Medical Embryology. 14th ed. Philadelphia: Wolters Kluwer, 2019. ttl.run.edu.ng
Mäkelä J.-A., Koskenniemi J. J., Virtanen H. E., Toppari J. Testis development // Endocrine Reviews. 2019. Vol. 40, No. 4. P. 857–905. doi:10.1210/er.2018-00140. OUP Academic
Shaw G., Renfree M. B., Wilson J. D. Wolffian duct development // Sexual Development. 2014. Vol. 8, No. 5. P. 273–280. doi:10.1159/000363432.
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