In the realm of ontology-based data access, the concept of query and predicate emptiness poses significant challenges that demand careful navigation. This paper explores the intricate landscape of empty queries and predicates, shedding light on their origins and implications. We delve into the complexities of ontology-based data access systems, presenting both theoretical underpinnings and practical considerations. Moreover, we offer a comprehensive examination of existing solutions, proposing novel strategies to address these issues. By providing a roadmap for handling query and predicate emptiness, this research aims to empower practitioners and researchers in optimizing ontology-driven data retrieval.