Alcoholic liver diseases (ALDs) represent one of the most pressing public health challenges worldwide, including in the Republic of Uzbekistan. Chronic and excessive consumption of alcoholic beverages leads to progressive liver damage, ranging from fatty liver to alcoholic hepatitis and ultimately liver cirrhosis. The liver, as the primary organ responsible for alcohol metabolism, is particularly vulnerable to the toxic effects of ethanol and its metabolites. This scientific article examines the prevalence, pathogenesis, clinical forms, socio-economic consequences, and preventive strategies of alcoholic liver diseases. The study is based on an analytical review of Uzbek medical literature, official health statistics, and preventive healthcare guidelines. The findings highlight the crucial role of primary prevention, reduction of alcohol consumption, early diagnosis, and public health education in mitigating the burden of alcoholic liver diseases. The article emphasizes the importance of integrated medical and social approaches to prevent ALDs and improve population health outcomes.

alcohol, alcoholic liver disease, fatty liver, hepatitis, cirrhosis, prevention, public health, epidemiology

Ministry of Health of the Republic of Uzbekistan. (2022). Guidelines for the prevention of liver diseases. https://ssv.uz

Karimov, B. A. (2021). Alcohol consumption and liver diseases. Medical Journal of Uzbekistan, 4(2), 45–52.

Abdullayev, S. M. (2019). Problems of chronic hepatitis and liver cirrhosis. Uzbek Medical Bulletin, 3, 12–18.

State Statistics Committee of the Republic of Uzbekistan. (2023). Public health indicators. https://stat.uz

Healthy Lifestyle Center of Uzbekistan. (2022). Harmful effects of alcohol. https://salomatlik.uz

Qodirov, D. B. (2018). Clinical diagnostics of liver diseases. Tashkent: Medical Publishing House.