Post-thrombotic syndrome (PTS) is a chronic complication that develops after deep vein thrombosis and is characterized by pain, edema, skin changes, and trophic disorders of the lower extremities. This article presents a comparative analysis of conventional (conservative and pharmacological) and modern (endovascular and minimally invasive) treatment methods for PTS. Current evidence from recent clinical studies and systematic reviews was analyzed to evaluate treatment effectiveness. The findings indicate that while conservative therapy can reduce symptoms in mild to moderate cases, modern endovascular interventions demonstrate superior clinical outcomes in patients with severe post-thrombotic disease.

post-thrombotic syndrome, deep vein thrombosis, compression therapy, endovascular treatment, venous stenting

Kahn SR. The post-thrombotic syndrome. Hematology Am Soc Hematol Educ Program. 2016.

Vedantham S. Interventional approaches to post-thrombotic syndrome. J Thromb Thrombolysis. 2015.

Enden T, et al. Long-term outcome after catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis. Lancet. 2012.

Neglén P, Raju S. Intravascular ultrasound evaluation of venous obstruction. J Vasc Surg. 2002.

Kahn SR, et al. Compression stockings to prevent post-thrombotic syndrome. Lancet. 2014.