Articles | Open Access | https://doi.org/10.55640/

ENDOCRINE DISORDERS AND THEIR IMPACT ON GROWTH AND DEVELOPMENT IN CHILDREN

William I.K. , Medical researcher in Traumatology,traumatology centre.

Abstract

Endocrine disorders in childhood represent a significant medical and public health concern due to their profound impact on physical growth, pubertal development, and overall health. Hormonal imbalances affecting the growth hormone, thyroid hormones, adrenal hormones, and insulin play a critical role in regulating normal growth and developmental processes. This article analyzes the effects of common pediatric endocrine disorders on growth patterns and developmental outcomes in children. Particular attention is given to growth hormone deficiency, hypothyroidism, diabetes mellitus, and disorders of puberty. The review highlights pathophysiological mechanisms, clinical manifestations, and the importance of early diagnosis and timely intervention. Understanding the influence of endocrine dysfunction on child development is essential for improving long-term health outcomes and quality of life.

Keywords

Endocrine disorders, children, growth impairment, development, growth hormone deficiency, pediatric endocrinology

References

Brook, C. G. D., & Clayton, P. E. (2012). Clinical pediatric endocrinology (6th ed.). Wiley-Blackwell.

Sperling, M. A. (2014). Pediatric endocrinology (4th ed.). Elsevier.

Rogol, A. D., Clark, P. A., & Roemmich, J. N. (2000). Growth and pubertal development in children and adolescents. Journal of Clinical Endocrinology & Metabolism, 85(12), 4631–4638.

Savage, M. O., et al. (2016). Growth hormone deficiency in childhood. Endocrine Reviews, 37(2), 123–156.

Rose, S. R., & Brown, R. S. (2006). Update of newborn screening and therapy for congenital hypothyroidism. Pediatrics, 117(6), 2290–2303.

Soliman, A. T., De Sanctis, V., & Kalra, S. (2014). Growth and development in children with diabetes mellitus. Indian Journal of Endocrinology and Metabolism, 18(1), S1–S5.

Palmert, M. R., & Dunkel, L. (2012). Delayed puberty. New England Journal of Medicine, 366(5), 443–453.

Carel, J. C., & Léger, J. (2008). Precocious puberty. New England Journal of Medicine, 358(22), 2366–2377.

Wit, J. M., et al. (2019). Growth disorders in childhood. Nature Reviews Endocrinology, 15(10), 577–589.

Cohen, L. E. (2018). Endocrine causes of short stature. Pediatric Clinics of North America, 65(1), 1–15.

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ENDOCRINE DISORDERS AND THEIR IMPACT ON GROWTH AND DEVELOPMENT IN CHILDREN. (2026). International Journal of Medical Sciences, 6(02), 261-263. https://doi.org/10.55640/