Articles
| Open Access |
https://doi.org/10.55640/
BENIGN PROSTATIC HYPERPLASIA
Bobokulov Nurillo Asatovich,Zayniddinov Mahmudjon Farxodjon o'g'li,Movlanov Hazrat Musulmon o'g'li , Samarkand State Medical University,Samarkand State Medical University,Samarkand State Medical UniversityAbstract
 Benign prostatic hyperplasia is a common urological condition in older men characterized by the excessive growth of glandular and stromal tissues of the prostate. This condition leads to lower urinary tract symptoms such as obstructive and irritative manifestations, including slow urine flow, difficulty initiating urination, frequent urination, nocturia, and occasional urinary incontinence. BPH significantly affects patients’ quality of life, sleep patterns, and daily activities, and may contribute to psychological stress. The pathogenesis of BPH involves complex interactions between hormonal changes, particularly testosterone and dihydrotestosterone, genetic predisposition, inflammatory processes, and impaired microcirculation. Early diagnosis, effective management strategies, lifestyle modifications, and preventive measures are essential to slow disease progression, improve patient outcomes, and reduce the medical and social burden associated with the condition. This study aims to review the etiology, clinical manifestations, diagnostic approaches, and treatment options for BPH while emphasizing the importance of patient-centered care and preventive strategies.
Keywords
Benign prostatic hyperplasia, Lower urinary tract symptoms, Obstructive symptoms, Irritative symptoms, Testosterone, Dihydrotestosterone, Diagnosis, Treatment, Quality of life.
References
Anderson JB, Gupta N, Tan WS. Comparative effectiveness of alphablockers in the management of lower urinary tract symptoms secondary to benign prostatic hyperplasia. Urology Journal. 2018;15(4):229236.
Bartsch G, Rittmaster R, Roehrborn CG. Pathophysiology of benign prostatic hyperplasia and therapeutic implications. Nature Reviews Urology. 2019;16(5):292306.
Chen L, Zhang H, Wang S. Regenerative medicine in benign prostatic hyperplasia: Emerging molecular and cellular approaches. Frontiers in Urology. 2024;4(1):112124.
Elshal AM, Elmansy HM, Kallidonis P. Laser enucleation of the prostate: Current perspectives and future directions. Current Opinion in Urology. 2023;33(2):8795.
Anderson, J. B., Gupta, N., & Tan, W. S. (2018). Comparative effectiveness of alphablockers in the management of lower urinary tract symptoms secondary to benign prostatic hyperplasia. Urology Journal, 15(4), 229236
Chen, L., Zhang, H., & Wang, S. (2024). Regenerative medicine in benign prostatic hyperplasia: Emerging molecular and cellular approaches. Frontiers in Urology, 4(1), 112124.
Elshal, A. M., Elmansy, H. M., & Kallidonis, P. (2023). Laser enucleation of the prostate: Current perspectives and future directions. Current Opinion in Urology, 33(2), 8795.
Gilling, P. J., Barber, N. J., & Bidair, M. (2022). Fiveyear outcomes for aquablation versus TURP in the management of benign prostatic hyperplasia: A randomized controlled trial. European Urology, 81(3), 345354.
Article Statistics
Downloads
Copyright License

This work is licensed under a Creative Commons Attribution 4.0 International License.