This article provides a comprehensive review of regenerative technologies in dentistry, focusing on autologous blood-derived products, Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF). It discusses their preparation techniques, clinical applications, dosage, efficacy, and limitations. PRP and PRF, rich in growth factors, stimulate cellular proliferation, angiogenesis, and collagen synthesis, promoting faster regeneration of bone and soft tissues. The article highlights their use in tooth extraction, implant placement, periodontal therapy, and oral surgery, emphasizing improved healing outcomes, reduced postoperative pain and inflammation, and enhanced tissue quality. Moreover, current research and innovative approaches combining PRP and PRF with advanced biomaterials and stem cell therapies are explored, indicating promising future directions in regenerative dentistry. Clinical evidence demonstrates that PRF and PRP are effective, safe, and increasingly integral to modern dental surgical practice.

PRF, PRP, dentistry, regenerative technology, bone regeneration, soft tissue regeneration, tooth extraction, implantology, periodontal therapy, growth factors, surgical dentistry, clinical efficacy.

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