Parkinson's disease (PD) is characterized not only by motor disorders, but also by a wide range of non-motor symptoms (NMS) that significantly affect the quality of life of patients. The aim of the study was to evaluate the effectiveness of dopamine receptor agonists (DRA) in correcting non-motor symptoms in PD patients. Sixty-nine patients with stage II–III disease were examined and divided into two groups: with and without DRA included in the treatment regimen. After 12 weeks of therapy, the main group showed a significant reduction in the severity of non-motor symptoms and depression and an improvement in quality of life indicators compared to the control group. The data obtained confirm the clinical feasibility of using DRA to correct non-motor manifestations of PD.

Parkinson's disease, non-motor symptoms, dopamine receptor agonists, depression, quality of life.

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