Pneumopathy is one of the main causes of mortality among newborns, as it causes systemic disorders associated with a lack of oxygen and blood supply. The aim of our work was to study in detail the structural changes in the kidneys of newborns who died in the neonatal period due to pneumopathy. We examined the kidneys of 20 such infants using standard histological staining methods (hematoxylin and eosin, van Gieson, toluidine blue) and morphometric analysis. As a result, severe circulatory disorders and degenerative processes were detected: glomerular plethora (in 76% of cases), granular degeneration of the tubular epithelium (in 82%), interstitial edema (in 70%) and venous stasis (in 68%). In addition, there was a statistically significant decrease in the height of the proximal tubular epithelium (p < 0.01) and an increase in the size of the renal corpuscle capsule (p < 0.05). These findings provide strong evidence that neonatal pneumopathy results in hypoxia- and ischemia-related renal damage.

newborns, pneumopathy, kidneys, hypoxia, morphometry, neonatal period.

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