Hemodialysis in children with acute renal failure (ARF) is often accompanied by pronounced psycho‑emotional stress, motor agitation, and decreased patient compliance. This may lead to complications during the procedure, displacement of vascular access, and reduced dialysis efficiency. Therefore, safe and controlled sedation is of great importance. In modern intensive care medicine, dexmedetomidine is one of the most widely used drugs with sedative and analgesic effects without significant respiratory depression. However, the features of its action when administered through different lines of the dialysis circuit remain insufficiently studied.

Dexmedetomidine, hemodialysis, arterial dialysis circuit line, venous dialysis circuit line

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