This article analyzes the biochemical mechanisms of oncogenesis in chronic kidney disease. It was shown that inflammation, oxidative stress, and impaired cellular metabolism in kidney tissue in patients with chronic kidney disease can create conditions for oncogenesis. Modern science seeks not only to identify and explain developmental phenomena, but also to control biological processes using regulatory mechanisms. Therefore, the morphology of the study of tissue and organ relationships is an urgent and promising direction. In chronic renal failure, the level of vascular endothelial growth factor is dangerous due to a decrease in glomerular filtration rate and the appearance of vascular stiffness. Therefore, chronic renal failure not only leads to impaired functioning of all organs and systems of the body, but also causes morphological changes in the spleen, which allows it to be classified as a disease of medical and social importance.

chronic kidney disease, renal functional reserve, glomerular filtration rate, antiplatelet agent, allthrombozepin, dipyridamole, edema, erythrocyturia, proteinuria, dysuria, nephrotic crisis, arthralgia, myalgia.

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