Articles | Open Access | https://doi.org/10.55640/

POST-COVID SYNDROME: CAUSES OF DEVELOPMENT, RISK FACTORS, MAIN PATHOGENETIC MECHANISMS AND MANIFESTATIONS

Xasanova Shahnoza Alisher qizi , PhD, Tashkent State Medical University

Abstract

Post-COVID syndrome (long COVID) is a complex of symptoms that persist after COVID-19 infection and significantly impact patients' quality of life. The aim of this study was to investigate the causes, risk factors, pathogenetic mechanisms, and clinical manifestations of post-COVID syndrome in 130 patients. Results revealed that the most common symptoms are chronic fatigue, shortness of breath, and cognitive impairment. A relationship was established between the severity of acute infection and the severity of post-COVID manifestations. The findings confirm the multifactorial nature of the disease and the need for a comprehensive approach to treatment.

Keywords

post-COVID syndrome, long COVID, SARS-CoV-2, patients, pathogenesis, risk factors, chronic fatigue.

References

World Health Organization. Post COVID-19 condition (Long COVID). 2023.

Nalbandian A. et al. Post-acute COVID-19 syndrome. Nature Medicine. 2021.

Carfì A., Bernabei R., Landi F. Persistent symptoms in patients after acute COVID-19. JAMA. 2022.

Huang C. et al. 6-month consequences of COVID-19. The Lancet. 2021.

Yong S.J. Long COVID or post-COVID-19 syndrome. Journal of Medical Virology. 2023.

Davis H.E. et al. Characterizing long COVID. ClinicalMedicine. 2025.

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POST-COVID SYNDROME: CAUSES OF DEVELOPMENT, RISK FACTORS, MAIN PATHOGENETIC MECHANISMS AND MANIFESTATIONS. (2026). International Journal of Medical Sciences, 6(03), 649-653. https://doi.org/10.55640/