The article presents a detailed epidemiological characterization of viral hepatitis A (VHA) in the Republic of Karakalpakstan for the 2017–2024. A retrospective analysis of morbidity dynamics by age groups was conducted. A wave-like pattern of the epidemic process was established, with a decrease in incidence rates in 2020–2021 and the formation of a new rise in 2023–2024. It was revealed that the main proportion of cases occurs among children aged 1–5 and 6–14 years. The obtained results indicate the need to strengthen preventive and sanitary-hygienic measures.

Hepatitis A, epidemiology, incidence, children, Karakalpakstan, dynamics.

World Health Organization. Hepatitis A Fact Sheet. 2023.

WHO. Global Hepatitis Report. 2022.

CDC. Hepatitis A Surveillance Report. 2023.

Jacobsen KH, Wiersma ST. Hepatitis A epidemiology. Vaccine. 2020.

Franco E et al. Hepatitis A: epidemiology and prevention. Lancet Infect Dis. 2021.

Lemon SM et al. Type A viral hepatitis: epidemiology. J Infect Dis. 2018.Vol.218, p. 1-10.

Jacobsen KH. The global prevalence of hepatitis A virus infection. Int J Infect Dis. 2019. Vol.85, p.16-22.

European Centre for Disease Prevention and Control. Hepatitis A Annual Report. 2022. p.5-18.

Bramer CA et al. Decline in infectious diseases during COVID-19. MMWR. 2020. Vol. 69, p. 1236–1240.

Sakamoto H et al. Impact of COVID-19 on communicable diseases. Lancet Reg Health. 2022. Vol. 12, p. 100–108.

Vizzotti C et al. Shifts in hepatitis A epidemiology. Vaccine. 2020. Vol. 38, p. 5670–5675.

Heymann DL. Control of Communicable Diseases Manual. 2022. p. 250–255.

WHO Regional Office for Europe. Hepatitis A epidemiology in transition. 2021. p. 12–27.

Karimov U et al. Viral hepatitis trends in Central Asia. // Central Asian Journal of Medicine. 2023. — Vol. 5, p. 45–52.

Кузин С.Н. Эпидемиология вирусных гепатитов. М.: ГЭОТАР-Медиа, 2020. — с. 45–60.