Articles | Open Access | https://doi.org/10.55640/

PARASITIC DISEASES OF THE BRAIN: CLINICAL CHARACTERISTICS, DIAGNOSTIC APPROACHES, AND THERAPEUTIC CHALLENGES.

Khushbokova Sarvinoz Shavkatovna , First-year Master’s Student, Termez Branch of Tashkent State Medical University

Abstract

Parasitic infections of the central nervous system (CNS) represent a critical challenge in modern neurology and global public health. This article provides a high-level analysis of the most prevalent neuroparasitic conditions, including neurocysticercosis, cerebral toxoplasmosis, and hydatid disease. By examining the transition from latent infection to symptomatic neurological crisis, the study highlights the importance of the blood-brain barrier (BBB) integrity and the host’s immunological response. The article evaluates current neuroimaging modalities and pharmacological regimens, advocating for a risk-stratified approach to treatment that balances antiparasitic efficacy with the management of secondary inflammatory cerebral edema.

Keywords

Neuroparasitology, Neurocysticercosis, Cerebral Toxoplasmosis, CNS infections, Neuroimaging, Albendazole, Intracranial Hypertension.

References

White, A. C., et al. (2020). Clinical Practice Guidelines for the Diagnosis and Management of Neurocysticercosis. Clinical Infectious Diseases.

Garcia, H. H. (2025). Neuroparasitology: Emerging Trends and Management. Journal of Neurology & Psychiatry.

Sotelo, J., & Del Brutto, O. H. (2023). Antiparasitic Treatment in Neurocysticercosis. Lancet Neurology.

Nash, T. E., & O’Connell, E. M. (2024). Subarachnoid Neurocysticercosis: A Review of Clinical and Imaging Characteristics.

World Health Organization. (2024). Global Status Report on Neglected Tropical Diseases.

Central Asian Medical Journal. (2025). Echinococcosis of the Brain: A Regional Study.

Del Brutto, O. H. (2022). Diagnostic Criteria for Neurocysticercosis: A Revised Proposal.

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PARASITIC DISEASES OF THE BRAIN: CLINICAL CHARACTERISTICS, DIAGNOSTIC APPROACHES, AND THERAPEUTIC CHALLENGES. (2026). International Journal of Medical Sciences, 6(4), 206-208. https://doi.org/10.55640/