Coronary artery disease (CAD) and its most severe manifestation, myocardial infarction (MI), remain the leading causes of global mortality. While traditional risk factors (hypertension, smoking, diabetes) are well-known, they do not fully explain why some individuals with "ideal" profiles suffer premature MI.

Personalized Medicine, Polygenic Risk Score (PRS), Myocardial Infarction Prevention, Pharmacogenomics, Genome-Wide Association Studies (GWAS), Precision Cardiology, Genetic Profiling, Cardiovascular Risk Assessment

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