Stress-induced cardiomyopathy (SIC), widely known as Takotsubo Syndrome (TTS), has evolved from a perceived benign condition into a complex acute cardiac syndrome with significant morbidity and mortality. Characterized by transient left ventricular apical ballooning, its clinical presentation frequently mimics acute myocardial infarction (AMI). In the last decade, and particularly in the post-pandemic era (2020–2026), the global incidence of TTS has seen a documented surge, necessitating a deeper understanding of the neuro-cardiac axis.

Takotsubo Syndrome, Stress-Induced Cardiomyopathy, Brain-Heart Axis, Catecholamine Storm. Neuro-cardiology, Left Ventricular Apical Ballooning, Post-Pandemic Cardiology, Psychosomatic Medicine. InterTAK Diagnostic Score, Precision Medicine, Myocardial Stunning, Heart Rate Variability (HRV).

Templin, C., Ghadri, J. R., Diekmann, J., et al. (2015). Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy. New England Journal of Medicine, 373(10), 929-938. (Bu maqola InterTAK registrining asosi hisoblanadi).

Ghadri, J. R., Wittstein, I. S., Prasad, A., et al. (2018). International Expert Consensus Document on Takotsubo Syndrome (Part I and II): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology. European Heart Journal, 39(22), 2032-2062.

Medina de Chazal, H., Del Buono, M. G., Keyser-Marcus, L., et al. (2018). Stress-Induced Cardiomyopathy: From Connection Between the Heart and Mind to Clinical Management. JACC (Journal of the American College of Cardiology), 71(13), 1450-1472.

Pelliccia, F., Kaski, J. C., Crea, F., & Camici, P. G. (2017). Pathophysiology of Takotsubo Syndrome. Circulation, 135(24), 2426-2441.

Jabri, A., Kalra, A., Kumar, A., et al. (2020). Incidence of Stress Cardiomyopathy During the COVID-19 Pandemic. JAMA Network Open, 3(7), e2014780. (Pandemiya davridagi o'sish haqida eng muhim manba).

Omerovic, E., Citro, R., Ahlsson, A., et al. (2022). European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy Position Paper on Takotsubo Syndrome. European Heart Journal - Cardiovascular Pharmacotherapy, 8(1), 82-95.

Singh, T., Khan, H., Misadghi, A., et al. (2022). Takotsubo Syndrome: Pathophysiology, Emerging Concepts, and Clinical Management. Current Problems in Cardiology, 47(11), 101049.

Napp, L. C., & Bauersachs, J. (2020). Takotsubo Syndrome: Between Evidence and Speculation. Nature Reviews Cardiology, 17(1), 27-36.

Kuratani, K., et al. (2023). Long-term Prognosis of Takotsubo Syndrome vs. Acute Myocardial Infarction: A 10-Year Follow-up Study. Journal of Cardiology Clinical Reports.

Cammann, V. L., et al. (2024). The Genetic Basis of Takotsubo Syndrome: New Insights from Genome-Wide Association Studies. Circulation: Genomic and Precision Medicine. (Genetik moyillik bo'yicha eng so'nggi tadqiqot).

D’Ascenzo, F., et al. (2021). Machine Learning for Predicting In-hospital Complications in Patients with Takotsubo Syndrome. European Heart Journal - Digital Health.

Scally, C., et al. (2019). Myocardial Inflammation in Takotsubo Syndrome as Measured by Cardiac Magnetic Resonance Imaging and Cardiac Biomarkers. Circulation, 140(13), 1111-1119.