Articles
| Open Access |
https://doi.org/10.55640/
MOLECULAR DOCKING ANALYSIS TO EVALUATE THE WOUND HEALING POTENTIAL OF CALANHOE DAIGREMONTIANA EXTRACT
Mirxalikova M.B1, Mamadrahimov A.A1, Jalilov M.K2, Abduxoliqov F2, Kuchkarov N.Y3 , 1PhD Student, National University of Uzbekistan, Tashkent, Uzbekistan / 1Institute of Bioorganic Chemistry, Tashkent, UzbekistanAbstract
The purpose of this work is to study the extracted formation of Calanhoe Daigremontiana, to establish their flavonoid formation, to determine the physicochemical characteristics and wound-healing activity. The experimental object of the study: in order to study pharmacological activity, Calanhoe Degremontiana plant was used, collected during the winter period in January 2026 on the territory of the Republic of Uzbekistan (Tashkent). Flavonoid composition was determined by using High Performance Liquid Chromatography – Diode Array Detector (HPLC-DAD). The molecular docking method was used to examine the active components based on their ability to interface with the target protein.
Keywords
Calanhoe Daigremontiana, Wound Healing activity, HPLC-DAD, Molecular Docking,
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