This article analyzes the histological changes occurring in large and medium-sized blood vessels during the process of atherosclerosis, which is the leading cause of cardiovascular system diseases. Morphological changes at the cellular and tissue levels observed in the tunica intima, media, and adventitia layers of the blood vessel wall are elucidated.

Histology, atherosclerosis, endothelial dysfunction, foam cells, tunica intima, smooth muscle cells.

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