Articles
| Open Access |
https://doi.org/10.55640/
"LABORATORY BIOCHEMICAL PARAMETERS AND THEIR IMPACT ON ORGANS AND SYSTEMS IN RATS WITH LOW AND HIGH LEVELS OF EMOTIONAL REACTIVITY"
Z.Ch. Kurbanova,D.B. Akhmedova,Z.A. Sayfudinova,Nargiza Maratovna Bolegenova , Head of Department,DSc Professor,Scientific Supervisor:DSc Associate Professor,PhD Associate Professor, Master’s Student in Laboratory Medicine, Tashkent State Medical UniversityAbstract
This scientific article investigates the laboratory characteristics of biochemical parameters in rats with low and high levels of emotional reactivity. Furthermore, it identifies the biochemical properties of hormones, neurotransmitters, neuropeptides, and cytokines secreted during emotional changes in the subjects, while demonstrating their physiological effects on various organs and systems.
Keywords
Organ, System, Hormones, LER (Low Emotional Reactivity), HER (High Emotional Reactivity), Stress, Excretory, Secretory, Metabolism, Reaction, Cortisol, Neurotransmitter, Neuropeptide, Cytokine.
References
Зубков А.Н. Физиология человека и животных. Москва: Мир, 2012.
(Markaziy nerv tizimi, endokrin va stress reaksiyalari bo‘yicha asosiy darslik)
Селье Г. Стресс без дистресса. Москва: Прогресс, 1982.
(Stress nazariyasining klassik asoslari)
Судаков К.В. Системная организация физиологических функций. Москва: Медицина, 2000.
(Nerv va gormonal tizimlarning integrativ faoliyati)
Агаджанян Н.А., Тупицын И.О. Основы физиологии человека. Москва: ГЭОТАР-Медиа, 2015.
(Stress, gormonlar va neyrofiziologik jarayonlar)
Каримов М.М. Tibbiy biokimyo asoslari. Toshkent: Ibn Sino nomidagi nashriyot, 2018.
(Biokimyoviy parametrlar va metabolik jarayonlar)
Рахимов А.Р. Biologik kimyo va molekulyar biologiya. Toshkent: O‘qituvchi, 2016.
(Neyromediatorlar va hujayra biokimyosi)
Курбанов Ш.К., Исмоилов Ж.А. Odam va hayvonlar fiziologiyasi. Toshkent: O‘zbekiston Milliy universiteti nashriyoti, 2019.
(Markaziy Osiyo ta’lim tizimi uchun asosiy fiziologiya manbasi)
McEwen B.S. (2007). Physiology and neurobiology of stress and adaptation: Central role of the brain. Physiological Reviews, 87(3), 873–904.
Sapolsky R.M. (2004). Why Zebras Don’t Get Ulcers. New York: Holt Paperbacks.
Krukoff T.L. (2015). Stress and the brain: neuroendocrine mechanisms. Journal of Neuroendocrinology, 27(6), 441–452.
Porsolt R.D., Anton G., Blavet N., Jalfre M. (1977). Behavioural despair in rats: a new model sensitive to antidepressant treatments. European Journal of Pharmacology, 47(4), 379–391.
Carobrez A.P., Bertoglio L.J. (2005). Ethological and temporal analyses of anxiety-like behavior: The elevated plus-maze model. Nature Protocols, 3(9), 1467–1476.
McLean J.H., Nakane H. (1974). Periodicity of monoamine oxidase activity in brain and its relation to behavior. Brain Research, 74(1), 1–14.
Anisman H., Zacharko R.M. (1992). Depression as a risk factor for immunological disorders. Immunology Today, 13(2), 53–58.
Guyton A.C., Hall J.E. (2016). Textbook of Medical Physiology. Elsevier.
O‘zbekiston Respublikasi Sog‘liqni saqlash vazirligi (2021). Tibbiy biologiya va fiziologiya asoslari. Toshkent.
Toshkent Tibbiyot Akademiyasi (TTA) (2020). Normal va patologik fiziologiya darsligi. Toshkent.
O‘zbekiston Milliy universiteti (2022). Biologiya va genetika asoslari. Toshkent.
O‘zbekiston Fanlar akademiyasi (2019). Biologik tadqiqotlar va eksperimental tibbiyot ishlari to‘plami. Toshkent.
Article Statistics
Downloads
Copyright License

This work is licensed under a Creative Commons Attribution 4.0 International License.