Arterial hypertension (AH) is one of the most pressing problems in modern medicine, serving as a major risk factor for cardiovascular diseases and mortality rates. This scientific article aims to analyze the pathogenesis of arterial hypertension and the impairment of physiological regulatory mechanisms that control blood pressure (sympathetic nervous system, renin-angiotensin-aldosterone system, kidneys, and endothelial function). The elevation of blood pressure is a multifactorial process resulting from sequential and interconnected dysfunctions within the homeostatic system.

Arterial hypertension, pathogenesis, renin-angiotensin-aldosterone system (RAAS), sympathetic nervous system, endothelial dysfunction, homeostasis, pressure natriuresis.

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