The relevance of noncompaction cardiomyopathy (NCCM) in children is обусловed by a number of clinical, diagnostic, and prognostic factors that have increasingly attracted the attention of pediatricians and pediatric cardiologists in recent years [3,5]. Noncompaction cardiomyopathy is a rare but potentially life-threatening form of cardiomyopathy characterized by impaired normal embryonic myocardial compaction, resulting in prominent trabeculation and deep intertrabecular recesses. Despite its relative rarity, this condition is being diagnosed more frequently due to the widespread use of modern imaging techniques such as echocardiography and cardiac magnetic resonance imaging [1,6,9].

NCCM is of particular significance in the pediatric population, as its clinical manifestations are highly variable, ranging from an asymptomatic course to severe heart failure, life-threatening arrhythmias, and thromboembolic complications. In children, the disease often presents at an early age and may lead to disability or death [2,5,7].

Recent studies, including those by the authors of this article (2022; 2026), emphasize that the clinical course of noncompaction myocardium in children is characterized by marked polymorphism of symptoms and varying degrees of hemodynamic impairment, which complicates early diagnosis and necessitates in-depth clinical and instrumental evaluation. Their findings indicate that left ventricular noncompaction (LVNC) is often detected incidentally or at the stage of already established heart failure, underscoring the need for more detailed investigation of the clinical aspects of this condition [1,4,7].

The absence of specific clinical signs in the early stages makes timely diagnosis difficult, thereby increasing the risk of an unfavorable prognosis [2,8,10].

Diagnostic challenges in NCCM are also associated with the lack of universally accepted criteria, especially in pediatric practice. Different echocardiographic and MRI criteria may yield inconsistent results, leading to both overdiagnosis and underestimation of the true prevalence of the disease. This highlights the need to improve diagnostic approaches and develop clear clinical guidelines [1,3,6].

Thus, noncompaction cardiomyopathy in children represents a relevant medical problem requiring further investigation. The need for early diagnosis, clarification of pathogenetic mechanisms, development of unified diagnostic criteria, and optimization of treatment strategies determines the importance of conducting scientific research in this field and implementing its results into clinical practice.

Objective. To evaluate and analyze the clinical manifestations of left ventricular noncompaction in children.

The study was conducted at the cardiology department and the functional diagnostics department of the Andijan Regional Children’s Multidisciplinary Medical Center. The study included 20 children aged 8 to 16 years with a verified diagnosis of noncompaction cardiomyopathy (NCCM).

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