This article analyzes the stages of formation of pharmacoeconomics, its emergence as a scientific direction, and its role in the healthcare system. Pharmacoeconomics is defined as a science aimed at the rational use of medical resources, the economic assessment of the effectiveness and safety of medicines, as well as the harmonization of clinical and economic indicators in the choice of treatment methods. The article highlights the main stages of pharmacoeconomics development - the emergence of clinical and economic analysis, the formation of "cost-effectiveness," "cost-benefit," and "cost-benefit" analysis methods, as well as their integration with evidence-based medicine. It also reveals the importance of pharmacoeconomic assessment in the processes of drug policy, medical insurance, regulation of the pharmaceutical market and public procurement in the modern healthcare system. The research results indicate that pharmacoeconomics plays a crucial role in ensuring financial stability within the healthcare system, improving the quality of medical services for the population, and ensuring the fair distribution of resources. The development of this direction serves to scientifically substantiate the medical decision-making process and is an important factor in improving healthcare policy.

Pharmaceutical economics, healthcare economics, cost-effectiveness analysis, cost-benefit analysis, cost-benefit analysis.

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