Articles | Open Access | https://doi.org/10.5281/zenodo.20143016

“DIABETES MELLITUS: CAUSES, TREATMENT METHODS, AND MICROBIOLOGICAL FOUNDATIONS”

Djurayeva Muxabbat Ergashovna, Ergashov Diyorbek Orifjon ugli, Yuldoshov Shuhrat Ulmasjon ugli , Teacher of Termez branch of Tashkent State Medical University, Students of Termez branch of Tashkent State Medical University

Abstract

 This article comprehensively discusses the etiology, pathogenesis, clinical forms, modern treatment methods, and microbiological foundations of diabetes mellitus. Today, diabetes mellitus is considered one of the chronic metabolic diseases posing a serious threat to the health of the global population. The disease occurs as a result of insulin deficiency or decreased tissue sensitivity to insulin and is characterized by hyperglycemia. The article scientifically analyzes the mechanisms of development of type 1 and type 2 diabetes, the role of hereditary and external factors, intestinal microbiota, and the significance of microorganisms in the development of diabetes. In addition, streptococcal infections occurring in diabetes, impaired wound healing, diabetic foot syndrome, and changes in the immune system are also examined. Modern treatment methods, insulin therapy, glucose-lowering medications, diet therapy, physical activity, and preventive measures are described in detail. The article highlights the importance of a healthy lifestyle and regular medical supervision in preventing diabetes and reducing its complications.

Keywords

Diabetes mellitus, insulin, hyperglycemia, insulin resistance, microbiota, streptococcal infection, diabetic foot, metabolic disorder, autoimmune process, glucose, HbA1c, diet therapy, microangiopathy, immune system, diabetic complications.

References

Dedov I.I., Shestakova M.V. Diabetes Mellitus: Diagnosis, Treatment, Prevention. Moscow: GEOTAR-Media, 2021.

Akbarov Z.S. Internal Diseases and Endocrinology. Tashkent: Ibn Sino Publishing House, 2020.

Nurmukhamedova N.A. “Modern Aspects of Diabetes Mellitus Treatment.” Medical Journal of Uzbekistan, 2022, No. 4, pp. 45–52.

Shestakova M.V., Vikulova O.K. “Microvascular Complications of Diabetes Mellitus.” Problems of Endocrinology, 2021, Vol. 67(3), pp. 15–24.

Ismailov S.I. Clinical Endocrinology. Tashkent: Fan Publishing House, 2018.

Karimov H.Y., Yuldashev A.A. “Diabetic Foot Syndrome and Infectious Complications.” Uzbek Medical Journal, 2022, No. 6, pp. 88–94.

Tokhirova D.K. “Immunological Changes in Patients with Diabetes Mellitus.” Central Asian Journal of Medicine, 2021, Vol. 5(2), pp. 101–108.

Fadeev V.V. Clinical Endocrinology. Moscow: Practical Medicine, 2020.

Kholmatova F.M. “Diet Therapy in Type 2 Diabetes Mellitus.” Young Scientist of Uzbekistan, 2023, No. 1, pp. 33–38.

Alberti K.G.M.M., Zimmet P.Z. “Definition, Diagnosis and Classification of Diabetes Mellitus.” Diabetic Medicine, 2019, Vol. 15(7), pp. 539–553.

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“DIABETES MELLITUS: CAUSES, TREATMENT METHODS, AND MICROBIOLOGICAL FOUNDATIONS”. (2026). International Journal of Medical Sciences, 6(5), 440-444. https://doi.org/10.5281/zenodo.20143016