The study involved 30 patients, 17 of whom formed the main group and received the immunostimulant Derinat in the postoperative period, the effect of which normalized the indices of local and general immunity of patients with polypous ethmoiditis, and also reduced the number of relapses. The significantly low level of IgA after treatment increased to control values, the content of the reduced level of IgG normalized, and the high level of IgM significantly decreased to the control value.

immune status, polypous ethmoiditis, Derinat.

Dobrynin K.B. Portenko, S.A. Yurkin et al. Modern trends in anti-relapse treatment of polypous rhinosinusitis // Problems of rehabilitation in otolaryngology. Samara, 2013. - P. 240-242.

Lopatin A.S., Sidorenko I.V., Zakharzhevskaya T.V. et al. Efficiency of nasonex in the treatment of allergic rhinitis and chronic polypous rhinosinusitis // Zh. Vest. Otorhinolaryngologiya. 2020. - No. 4.- P. 60-63.

Mohsen Ya.S., Belyaev A.N., Kozlov S.A., Baytyakov V.V. Pathogenetic correction of endotoxicosis in polypous rhinosinusitis // International Journal of Applied and Fundamental Research 2010.-№1.- P.11

Palchun V.T., Romanova O.N., Polyakova T.S., Bondareva G.P. Modern aspects of polypous rhinosinusitis JJ Vestn. otolaryngologists. Proc. Rus. conf., otolaryngologists, November 18-19, 2013 – P.133-134.

Ryazantsev S.V. Modern views on the therapy of polypous rhinosinusitis. Medical almanac.-2018.-№3.- P.43-45.